KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13
All Species:
22.12
Human Site:
S583
Identified Species:
40.56
UniProt:
Q9UHV7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHV7
NP_005112.2
2174
239318
S583
E
D
R
I
D
S
L
S
Q
S
F
P
P
Q
Y
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
S597
E
D
R
I
D
S
L
S
Q
S
F
P
P
Q
Y
Rhesus Macaque
Macaca mulatta
XP_001110128
2174
239364
S583
E
D
R
I
D
S
L
S
Q
S
F
P
P
Q
Y
Dog
Lupus familis
XP_537704
2182
240593
S592
E
D
R
I
D
S
L
S
Q
S
F
P
A
Q
F
Cat
Felis silvestris
Mouse
Mus musculus
Q5SWW4
2171
238573
S583
E
D
R
I
D
S
L
S
Q
S
F
P
P
P
F
Rat
Rattus norvegicus
NP_001100505
2040
223488
K488
N
V
A
W
K
Y
Y
K
V
P
K
K
K
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
S579
E
D
R
I
D
S
L
S
Q
P
F
P
A
Q
F
Chicken
Gallus gallus
XP_415884
2225
244861
R627
P
T
K
T
M
E
D
R
L
D
G
L
S
Q
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
M529
L
H
S
S
A
D
E
M
A
G
S
P
Q
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
K654
P
I
D
H
L
L
D
K
N
T
P
A
P
T
P
Honey Bee
Apis mellifera
XP_393643
1982
216109
S430
V
P
A
N
A
P
R
S
V
L
N
R
T
E
A
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
N715
P
I
T
Y
L
T
N
N
V
D
N
N
D
F
E
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
97.7
94.1
N.A.
92.5
87.8
N.A.
89.5
84.6
N.A.
64.8
N.A.
24.7
35
21
25.7
Protein Similarity:
100
98.3
98.4
96
N.A.
96.4
91.2
N.A.
94
90.5
N.A.
76.9
N.A.
41.3
51.5
37.4
36
P-Site Identity:
100
100
100
86.6
N.A.
86.6
0
N.A.
80
6.6
N.A.
6.6
N.A.
6.6
6.6
0
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
0
N.A.
86.6
13.3
N.A.
6.6
N.A.
13.3
13.3
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
16
0
0
0
8
0
0
8
16
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
47
8
0
47
8
16
0
0
16
0
0
8
8
0
% D
% Glu:
47
0
0
0
0
8
8
0
0
0
0
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
47
0
0
8
24
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% G
% His:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
47
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
8
0
0
16
0
0
8
8
8
0
0
% K
% Leu:
8
0
0
0
16
8
47
0
8
8
0
8
0
0
0
% L
% Met:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
0
8
8
8
0
16
8
0
0
0
% N
% Pro:
24
8
0
0
0
8
0
0
0
16
8
54
39
16
24
% P
% Gln:
0
0
0
0
0
0
0
0
47
0
0
0
8
47
0
% Q
% Arg:
0
0
47
0
0
0
8
8
0
0
0
8
0
0
0
% R
% Ser:
0
0
8
8
0
47
0
54
0
39
8
0
8
0
0
% S
% Thr:
0
8
8
8
0
8
0
0
0
8
0
0
8
8
0
% T
% Val:
8
8
0
0
0
0
0
0
24
0
0
0
0
0
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
8
0
0
0
0
0
0
0
24
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _